College of Natural and Social Sciences
Department of Chemistry & Biochemistry
Office
ASCB122D
Phone
323-343-2353
Email
ywang184@calstatela.edu
Associate Professor
Research Website: /research/nanoscale-electrochemistry
Research Interests:
Analytical Chemistry, Nanoscale electrochemistry, Scanning probe microscopy, Plasmonics based imaging and sensing techniques, Single entity analysis, Parkinson's Disease, Environmental Sciences
Teaching:
CHEM 3500 Quantitative Analysis
CHEM 4510 Advanced Analytical Chemistry: Optical Spectroscopy
CHEM 4520 Advanced Analytical Chemistry: Analytical Separations and Mass Spectrometry
CHEM 4530 Advanced Analytical Chemistry: Electrochemistry and Surface Techniques
CHEM 5000 Interdisciplinary Discoveries in Chemistry and Biochemistry
Educational Background:
Postdoctoral Research Associate, Biodesign Institute, Arizona State University, 2013-2016
Ph.D. in Chemistry, The City University of New York, New York, NY, 2007-2013
B. S. in Materials Chemistry, Peking University, Beijing, China, 2002-2006
Selected Publications:
(Please see Google Scholar Citation for a full list of publications, student authors from CSULA are highlighted in bold)
- W. Gaieck, A. Zhang, A. C. Sabatose, M. T. Ngo, E. Schwartz, W. White, S. Luo, L. Schulte, Y. Wang, S. Ardo "Teaching the concepts of Donnan potential and liquid junction potential by evaluating homemade pH and ionsensitive probes constructed using commercial ion exchange membranes and reference electrodes" J. Chem. Ed, submitted
- N. D'Antona, J. Kelly, N. Barnard, S. Ardo, Y. Wang, Y. Surendranath, T. E. Markland, P. A. Kempler*, S. Boettcher "Proton-Transfer Kinetics at Liquid-Liquid Interfaces" JACS, under revision
- S. Groysman, Y. Chen, A. Garcia, C. Martinez, K. Diego-Perez, M. Benavides, Y. Chen, Z. Wan, S. Wang, R. Liu, D. Wang, C. Liu*, Y. Wang* "Sensitive Imaging of Electroactive Species in Plasmonic Electrochemical Microscopy Enabled by Nanoconfinement" ACS Electrochemistry, 2025, DOI: 10.1021/acselectrochem.4c00227
- A. Garcia, C. Dhoj, S. Groysman, K. Wang, S. Vo, A. Anguiano, T. Tran, D. Jiang and Y. Wang* "Prussian blue nanofilm-sensitized plasmonic electrochemical microscopy for spatially resolved detection of the localized delivery of hydrogen peroxide" Sensor Actuator Rep 2024, 8, 100218, DOI: 10.1016/j.snr.2024.100218
- C. Dhoj, A. Garcia, A. Manasyan, M. Benavides, D. Abou Abbas, C. Toscano, E. Porter, and Y. Wang* "Scanning Ion Conductance Microscopy Reveals Differential Effect of PM2.5 Exposure on A549 Lung Epithelial and SH-SY5Y Neuroblastoma Cell Membranes" Anal. Bioanal. Chem. 2023, 415, 4557–4567, DOI: 10.1007/s00216-023-04690-y
- S. G. Guillen, J. Parres-Gold, A. Ruiz, E. Lucsik, B. Dao, T. K. L. Hang, M. Chang, A. O. Garcia, Y. Wang*, and F. Tian* "pH-Responsive Metal–Organic Framework Thin Film for Drug Delivery"Langmuir 2022, 38 (51), 16014–16023
- C. Feng, M. Flores, C. Dhoj, A. Garcia, S. Belleca, D. Abou Abbas, J. Parres-Gold, A. Anguiano, E. Porter, and Y. Wang* "Observation of Alpha-Synuclein Pre-Formed Fibrils Interacting with SH-SY5Y Neuroblastoma Cells Membranes Using Scanning Ion Conductance microscopy" ACS Chem. Neurosci., 2022, 13 (24), 3547-3553
- B. A. Beadell, A. Chieng, K. R Parducho, Z. Dai, S. Ho, G. Fujii, Y. Wang, E. Porter* "Nano- and Macroscale Imaging of Cholesterol Linoleate and Human Beta Defensin 2-Induced Changes in Pseudomonas aeruginosa Biofilms" Antibiotics, 2021, 10 (11), 1279
- A. Garcia, K. Wang, F. Bedier, M. Benavides, Z. Wang, S. Wang, Y. Wang* "Plasmonic Imaging of Electrochemical Reactions at Individual Prussian Blue Nanoparticles" Front. Chem., 2021, 9, 718666
- A. Garcia, S. Wang, N. Tao, X. Shan*, Y. Wang* "Plasmonic Imaging of Oxidation and Reduction of Single Gold Nanoparticles and Their Surface Structural Dynamics" ACS Sens. 2020, 6 (2), 502-507
- J. Parres-Gold, A. Chieng, S. Wong Su, Y. Wang* “Real-Time Characterization of Cell Membrane Disruption by α-Synuclein Oligomers in Live SH-SY5Y Neuroblastoma Cells” ACS Chem. Neurosci., 2020, 11 (17), 2528-2534
- K. R Parducho, B. Beadell, T. Ybarra, M. Bush, E. Escalera, A. T. Trejos, A. Chieng, M. Mendez, C. Anderson, H. Park, Y. Wang, W. Lu, E. Porter* “The Antimicrobial Peptide Human Beta-Defensin 2 Inhibits Biofilm Production of Pseudomonas aeruginosa Without Compromising Metabolic Activity” Front Immunol, 2020, 11, 805
- M. Chang, G. Morgan, F. Bedier, A. Chieng, P. Gomez, S. Raminani, Y. Wang* “Recent advances in nanosensors built with pre-pulled glass nanopipettes and their applications in chemical and biological sensing” J. Electrochem. Soc., 2020, 167 (3), 037533
- Q. Liu, X. Wang*, A. Benedict, L. Janibekyan, S. Wong Su, Y. Wang*, F. Zhou* “Surface Plasmon Resonance Coupled with Potential-Step Chronoamperometry: Theory and Applications for Quantitative Measurements of Electrodeposited Thin Films”. Electroanalysis, 2019, 31, 1-8.
- A. Chieng, M. Chiang, K. Triloges, M. Chang and Y. Wang* “Recent progress in the studies of electrochemical interfaces by surface plasmon resonance spectroscopy and microscopy”, Curr. Opin. Electrochem. 2019, 13, 94.
- S. Wong Su, A. Chieng, J. Parres-Gold, M. Chang, Y. Wang* “Real-time determination of aggregated alpha-synuclein induced membrane disruption at neuroblastoma cells using scanning ion conductance microscopy” Faraday Discuss., 2018, 210, 131
- Y. Wang, D. Wang, M. V. Mirkin “Resistive-pulse and Rectification Sensing with Glass and Carbon Nanopipettes” invited article for Proc. R. Soc. A, 2017, 473, 20160931
- Y. Wang, X. Shan, S. Wang, N. Tao “Plasmonic Imaging of Surface Electrochemistry of Single Gold Nanowires”, J. Am. Chem. Soc., 2017, 139, 1376
- Y. Wang, X. Shan, N. Tao “Emerging Tools for Studying Single Entity Electrochemistry”, Faraday Discuss, 2016, 193, 9
- Y. Wang, X. Shan, S. Wang, N. Tao, P. Y. Blanchard, Y. Yu, K. Hu, and M. V. Mirkin “Imaging Local Electric Field Distribution by Plasmonic Impedance Microscopy” Anal. Chem. 2016, 88, 1547
- Y. Wang, X. Shan, F. Cui, J. Li, S. Wang, N. Tao, “Electrochemical Reactions in Sub-femtoliter-Droplets Studied with Plasmonics-based Electrochemical Current Microscopy” Anal. Chem. 2014, 87, 494
- Y. Wang, K. Kececi, M. V. Mirkin “Electron Transfer/Ion Transfer Mode of the Scanning Electrochemical Microscope (SECM)”, Chem. Sci., 2013 ,4, 3606
- Y. Wang, K. Kececi, M. V. Mirkin, V. Mani, N. Sardesai and J. F. Rusling “Resistive-Pulse Measurements with Nanopipettes: Detection of Au Nanoparticles and Nanoparticle-Bound Anti-peanut IgY”, Chem. Sci., 2013 ,4, 655
- Y. Wang, J.-M. Noel, J. Velmurugan, W. Nogala, M. V. Mirkin, С. Lu, M. G. Collignonl, F. Lemaître and C. Amatore “Nanoelectrodes for Determination of Reactive Oxygen and Nitrogen Species inside Biological Cells” Proc. Nat. Acad. Sci., 2012, 109, 11534.
- Y. Wang, T. Kakiuchi, F. Shigematsu and M. V. Mirkin “Kinetics of Ion Transfer at the Ionic Liquid/Water Nanointerface” J. Am. Chem. Soc., 2010, 132, 16945.
- Y. Wang, J. Velmurugan and M. V. Mirkin, P. J. Rodgers, J. Kim and S.Amemiya “Kinetic Study of Rapid Transfer of Tetraethylammonium at the 1,2-Dichloroethane/Water Interface by Nanopipet Voltammetry of Common Ions” Anal. Chem., 2010, 82, 77.
Funding:
NSF CCI (subcontract, 2022-2025)
NSF CAREER (PI, 2021-2026)
NIH Research Enhancement Award (R15, PI, 2020-2024, 2024-2027)
NSF-Major Research Instrumentation (PI, 2018-2021)
NSF CREST (Co-PI, 2022-2027)
La Kretz Environment Endowment (PI, 2018-2019)
NSF-PREM (seed grant PI, 2018-2019)
CSUPERB New Investigator Grant (PI, 2017-2019)
CSU RSCA (PI)